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KMID : 0378020080510050011
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New Medical Journal
2008 Volume.51 No. 5 p.11 ~ p.17
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Comparative Study about Risk of Cardiac Complication in Incomplete Kawasaki Disease
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Noh Jae-Ho
Lee Jae-Wook
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Abstract
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Purpose: The diagnosis of incomplete Kawasaki disease (KD) may be delayed due to lack of most of the clinical criteria, resulting in a high risk of cardiac complication. We examined clinical characteristics in these patients comparing typical KD for early recognition and treatment.
Methods: One hundred seventeen patients diagnosed with KD who were treated with intravenous immunoglogulin (IVIG) (2.0 g/kg) at Soonchunhyang university, Gumi hospital from May 2006 to April 2008 were included in this study. Among them all, incomplete KD patients was thirty two. And we performed retrospective analysis of clinical characteristics and echocardiographic findings based on medical records. The parameters of therapeutic effects were duration of fever after IVIG administration, incidence of unresponsive patients to single administration of IVIG, and development of transient dilatation or aneurysm of coronary arteries.
Results: There is no significant difference in the duration of fever after IVIG between the both group (incomplete KD group (IKD) 1.7±1.1 days, typical KD group (TKD) 1.8±1.1 days; P=0.588). The incidences of unresponsive patient to the single administration of IVIG were 6.3 percent, 5.9 percent in the each group. Transient dilatation of coronary arteries occurred 21.9 percent in IKD, and 5.9 percent in TKD. Prevalence of coronary aneurysm were 1 patient in IKD (1/32).
Conclusion: There was significant difference in transient dilatation of coronary arteries between incomplete KD group and typical KD group at the acute stage. Early diagnosis and early treatment may be prevented coronary aneurysm in incomplete KD.
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KEYWORD
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Incomplete Kawasaki disease, Coronary aneurysm
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